PLASMA THERAPY

PRP and PRF are methods based on the use of the patient’s own blood to stimulate tissue repair, improve skin quality, and activate regenerative processes. Although they share the same foundation, these technologies differ in composition, centrifugation method, and biological effects.

PRP — Platelet-Rich Plasma
PRP is a liquid form of plasma with a high concentration of platelets containing a large number of growth factors.

After injection into tissues, PRP helps:

• stimulate fibroblasts,
• improve microcirculation,
• activate collagen synthesis,
• accelerate tissue repair,
• improve the quality of skin and hair.

PRP contains:

• blood plasma,
• platelets,
• dissolved proteins,
• growth factors,
• a small number of leukocytes.

PRP contains very little:

• red blood cells,
• dense fibrin matrix.

How is PRP obtained?
PRP is produced using relatively high centrifugation speeds.
The main goal is to separate red blood cells and concentrate platelets in the plasma.

Where is PRP used?
In aesthetic medicine:

• skin rejuvenation,
• improvement of skin tone and texture,
• post-acne treatment,
• hair loss therapy,
• recovery after laser procedures and chemical peels.

In dentistry and surgery:

• acceleration of healing,
• support of soft tissue regeneration,
• implant procedures,
• post-operative recovery.

Fibrin Form of PRP
A thicker fibrin form can be obtained from classic liquid PRP.
To achieve this, the plasma is heated to approximately 50–55°C for 4–5 minutes. A denser fibrin structure forms, and the preparation becomes more viscous.

What is the fibrin form used for?

• tissue densification,
• improving skin quality,
• treatment of thin, atrophic skin,
• correction of small superficial defects,
• improving skin texture.

The fibrin matrix temporarily acts as:

• a biological scaffold,
• mechanical support for tissues.

Plasma Filler
A plasma filler is a denser form of autologous material obtained through thermal processing of plasma. The plasma is heated to approximately 70–75°C for about 5 minutes. This causes pronounced protein denaturation, the plasma acquires a gel-like structure, and an autologous “biofiller” is formed.
A plasma filler is not a classic filler like those based on hyaluronic acid. It acts as a scaffold for future tissue formation and stimulates dermal growth and thickening.

Plasma filler:

• is created entirely from the patient’s own blood,
• has excellent biocompatibility,
• carries a minimal risk of allergic reactions.

Plasma filler is used for:

• correction of fine wrinkles,
• improvement of skin quality,
• delicate volume restoration,
• treatment of the periorbital area,
• neck area,
• hands.

Duration of effect
The effect of a plasma filler usually lasts from several weeks to several months depending on:

• the treatment area,
• the patient’s metabolism,
• injection technique,
• volume of the product used.

Since the material is completely autologous, it gradually biodegrades.

PRF (Platelet-Rich Fibrin)
Unlike PRP, PRF is obtained using lower centrifugation speeds, which allows more platelets, leukocytes, fibrin, growth factors, and stem cells to remain in the preparation. This provides a longer and more natural release of active components into the tissues.

PRF contains:

• platelets,
• fibrin,
• leukocytes,
• growth and regenerative factors.

Indications for PRF:

• improvement of skin quality,
• stimulation of collagen production,
• recovery after aesthetic procedures,
• reduction of signs of aging,
• acceleration of tissue healing,
• implantation and surgical procedures in dentistry,
• enhancement of soft tissue regeneration.

PRF is a natural way to stimulate the body’s regenerative processes without the use of artificial components.

Contraindications to Plasma Therapy:

• acute inflammatory processes,
• active infections,
• oncological diseases,
• blood clotting disorders,
• severe autoimmune diseases,
• pregnancy and breastfeeding,
• uncontrolled diabetes mellitus,
• use of certain anticoagulants,
• significant skin inflammation in the treatment area.